Rising Global Burden of Infection-Related Female Infertility

A study by Nature reveals a significant increase in infertility cases among women aged 15–49 due to sexually transmitted infections (STIs) and maternal sepsis over the past three decades. From 1990 to 2021, the global age-standardised prevalence rate (ASPR) rose from 839.52 to 982.37 per 100,000 women, with an estimated annual percentage change (EAPC) of 0.26. Additionally, years lived with disability (YLDs) increased from 62.81 to 106.69 thousand, indicating a growing health burden.

Regional Disparities Highlighted

The burden of infection-related infertility is not uniform globally. Low socio-demographic index (SDI) regions, particularly Western Sub-Saharan Africa, exhibit the highest ASPR, reaching 1,925.52 per 100,000 women. Interestingly, while these regions have the highest prevalence, they also show the fastest decline in ASPR, with an EAPC of -1.17, suggesting some progress in addressing the issue.

Age-Related Trends

Infertility due to infections increases with age, peaking among women aged 40–44. This trend underscores the importance of early intervention and education to prevent infections that could lead to infertility later in life.

Projections to 2050

If current trends continue, the burden of infection-related female infertility is projected to rise further by 2050. This anticipated increase emphasises the need for sustained public health efforts to combat STIs and maternal infections globally.(Nature)

Implications for Public Health Policy

The study's findings highlight the critical need for targeted strategies to prevent and control infection-related infertility. Policymakers are urged to focus on improving sexual health education, increasing access to healthcare services, and addressing socio-economic factors that contribute to the spread of infections, especially in low-SDI regions.

For a more detailed exploration of the study and its methodologies, you can access the full article here: "Global burden of female infertility attributable to sexually transmitted infections and maternal sepsis: 1990–2021 and projections to 2050", published in Scientific Reports https://www.nature.com/